Ginger (Gingerol) as an Anti-Tumour Medicine
Keywords:
Ginger, Gingerols, Bioactive compounds, Anti-cancerousAbstract
Ginger is a spice that is renowned for its characteristic aromatic fragrance and pungent taste, with documented healing properties. The scientific community has probed into the biological validation of its extracts and isolated compounds including the gingerols, shogaols, zingiberene, and zingerone, through in-vitro and in-vivo studies.
Accordingly, this review highlights the mechanisms and therapeutics of ginger and its bioactive compounds focused on a anti-tumor and anti-cancerous context and these evidence are based on the (i) cytotoxic effect against cancer cell lines, (ii) enzyme inhibitory action, (iii) combination therapy with chemotherapeutic and phenolic compounds, (iv) possible links to the microbiome and (v) the use of nano-formulations of ginger bioactive compounds as a more effective drug delivery strategy in cancer therapy.
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